The IRS states that it may determine the tax for you if it does not receive a response. It also warns that penalties and interest may continue to accrue and that a refund owed to you may be delayed because of the unfiled return.
An IRS calculation may use wage, interest, dividend, brokerage, and other income information reported by third parties. It may not include every deduction, credit, business expense, dependent, filing-status benefit, or cost-basis figure available on a return prepared from complete records.
The IRS may later send Notice CP2566 showing proposed tax, penalties, and interest based on its information. That notice gives response options, but correcting the matter after the IRS has calculated the tax can take more work than filing an accurate return in response to CP518.
If a balance is eventually assessed and remains unpaid, the account can move into the IRS collection process. CP518 itself is not a levy notice and does not replace the later notices and rights that apply to collection action.